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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD20
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA780
- 标记物:
Vio Bright R720
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry
- 浓度:
1:50
- 抗体英文名:
CD20 Antibody, anti-human, REAfinity™
- 抗体名:
CD20 Antibody, anti-human, REAfinity™
- 规格:
30 tests in 60 µL
Identification and enumeration of CD20+ cells by flow cytometryClone REA780 recognizes the CD20 antigen, a non-glycosylated transmembrane protein of 33–37 kDa that is expressed on B lineage cells from the pre–B cell stage to the B cell lymphoblast stage. The antigen is further expressed on most malignant B cells. CD20 is not found on early B cell progenitors or plasma cells. Oligomers of CD20 form a Ca 2)+ channel and might function in the regulation of local responses during B cell activation. | Additional information: Clone REA780 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Countouriotis, T. B. et al. (2002) Cell surface antigen and molecular targeting in the treatment of hematologic malignancies. Stem Cells 20 (3): 215–229. | Polyak et al. (2002) CD20 Workshop Panel report. In: Leucocyte typing VII, Oxford University Press.: . | Lamprecht, B. et al. (2008) Aberrant expression of the Tʜ2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3alpha. Blood 112 (8): 3339–3347. | Maxwell, S. A. et al. (2009) 14-3-3zeta mediates resistance of diffuse large B cell lymphoma to an anthracycline-based chemotherapeutic regimen. J. Biol. Chem. 284 (33): 22379–22389.
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CD20 Antibody, anti-human, Vio® Bright R720, REAfinity™, 30 tests in 60 µL
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