- 询价
- Miltenyi Biotec
- 德国
- 130-122-754
- 2025年12月09日
- Flow cytometry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD186 (CXCR6)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA1193
- 标记物：
PE
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 抗体英文名：
CD186 (CXCR6) Antibody, anti-mouse, REAfinity™
- 抗体名：
CD186 (CXCR6) Antibody, anti-mouse, REAfinity™
- 规格：
30 µg in 200 µL
Identification and enumeration of CD186 (CXCR6)+ cells by flow cytometryClone REA1193 recognizes the mouse CD186 chemokine receptor, which is also known as Cxcr6 (receptor for the C-X-C chemokine CXCL16). CD186 is expressed by naive CD8 T cells, natural killer T cells, and a subset of memory CD4 T cells. | The chemokine CXCL16 is produced by dendritic cells (DCs) in lymphoid organ T cell zones and by cells in the splenic red pulp. It is reported, that CXCL16 plays a role in promoting interactions between DCs and CD8 T cells and in guiding T cell movements in the splenic red pulp.Furthermore, CXCL16 and CXCR6 play an essential role in the maintenance of cardiac allograft tolerance mediated by NKT cells. | Additional information: Clone REA1193 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Matloubian, M. et al. (2000) A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo. Nat Immunol 1 (4): 298–304. | Jiang, X. et al. (2005) Cutting edge: critical role of CXCL16/CXCR6 in NKT cell trafficking in allograft tolerance. J Immunol 175 (4): 2051–2055.
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文献支持
CD186 (CXCR6) Antibody, anti-mouse, PE, REAfinity™, 30 µg in 200 µL
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