- 询价
- Miltenyi Biotec
- 德国
- 130-098-418
- 2025年12月09日
- Flow cytometry, Mass cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD185 (CXCR5)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA103
- 标记物：
FITC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, Mass cytometry
- 浓度：
1:11
- 抗体英文名：
CD185 (CXCR5) Antibody, anti-human, REAfinity™
- 抗体名：
CD185 (CXCR5) Antibody, anti-human, REAfinity™
- 规格：
100 tests in 1 mL
Identification and enumeration of CD185 (CXCR5)+ cells by flow cytometryClone REA103 recognizes human CD185, which is a 42 kDa G-protein–coupled chemokine receptor and is also known as CXCR5, monocyte-derived receptor 15 (MDR15), or Burkitt lymphoma receptor-1 (BLR1). BLR-1 was originally identified on cells of Burkitt´s lymphoma and B cells. B cell attracting chemokine 1 (BCA-1), also known as B-lymphocyte chemoattractant (BLC) or CXCL13, is the ligand of CD185. It is further expressed on central memory CD4 T cells, T folicular helper cells, and on a migratory population of skin-derived dendritic cells. | Additional information: Clone REA103 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Bryant, V. L. et al. (2007) Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: predominant role of IL-21 produced by CXCR5+ T follicular helper cells. J Immunol 179: 8180–8190. | Chevalier, N. et al. (2011) CXCR5 expressing human central memory CD4 T cells and their relevance for humoral immune responses. J Immunol 186 (10): 5556–5568. | Förster, R. et al. (1994) Expression of the G-protein-coupled receptor BLR1 defines mature, recirculating B cells and a subset of T-helper memory cells. Blood 84: 830–840. | Saeki, H. et al. (2000) A migratory population of skin-derived dendritic cells expresses CXCR5, responds to B lymphocyte chemoattractant in vitro, and co-localizes to B cell zones in lymph nodes in vivo. Eur. J. Immunol. 30 (10): 2808–2814. | Förster, R. et al. (1996) A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell 87 (6): 1037–1047. | Farooq, F. et al. (2016) Circulating follicular T helper cells and cytokine profile in humans following vaccination with the rVSV-ZEBOV Ebola vaccine. Sci Rep 6: 27944. | García, M. et al. (2017) Peripheral T follicular helper cells make a difference in HIV reservoir size between elite controllers and patients on successful cART. Sci Rep 7 (1): 16799.
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CD185 (CXCR5) Antibody, anti-human, FITC, REAfinity™, 100 tests in 1 mL
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