- 询价
- Miltenyi Biotec
- 德国
- 130-109-597
- 2025年12月09日
- Flow cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD192 (CCR2)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA624
- 标记物：
PE-Vio 770
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:11
- 抗体英文名：
CD192 (CCR2) Antibody, anti-human, REAfinity™
- 抗体名：
CD192 (CCR2) Antibody, anti-human, REAfinity™
- 规格：
100 tests in 1 mL
Identification and enumeration of CD192 (CCR2)+ cells by flow cytometryClone REA624 recognizes the CD192 antigen, a G protein–linked seven transmembrane receptor, which is also known as C-C chemokine receptor type 2 (CCR2) or monocyte chemoattractant protein 1 receptor (MCP-1-R). Two spliced variants of CD192 (CD192A and CD192B) are expressed on peripheral monocytes and basophils as a result of alternate splicing of a single gene and differ at the C-terminal end. CD192 and its main ligand CCL2 have been implicated in a wide range of immunobiological processes and neuropathologies, including recruitment of monocytes and regulation of bone marrow homeostasis, as well as multiple sclerosis, HIV-associated dementia, Alzheimer’s disease, and neuropathic pain. | Additional information: Clone REA624 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Charo, I. F. et al. (1994) Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails. Proc. Natl. Acad. Sci. U.S.A. 91 (7): 2752–2756. | Wong, L. M. et al. (1997) Organization and differential expression of the human monocyte chemoattractant protein 1 receptor gene. Evidence for the role of the carboxyl-terminal tail in receptor trafficking. J. Biol. Chem. 272 (2): 1038–1045. | Henrich, T. J. et al. (2013) HIV-1 entry inhibitors: recent development and clinical use. Curr. Opin. Virol. 3 (1): 51–57.
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CD192 (CCR2) Antibody, anti-human, PE-Vio® 770, REAfinity™, 100 tests in 1 mL
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