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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD182 (CXCR2)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA208
- 标记物:
APC
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry
- 浓度:
1:50
- 抗体英文名:
CD182 (CXCR2) Antibody, anti-human, REAfinity™
- 抗体名:
CD182 (CXCR2) Antibody, anti-human, REAfinity™
- 规格:
100 tests in 200 µL
Identification and enumeration of CD182 (CXCR2)+ cells by flow cytometryClone REA208 recognizes CD182 (CXCR2), which belongs to the class of chemokine receptors specific for CXC chemokines. Chemokine receptors are G-coupled protein receptors (GPCR) with seven-transmembrane domains and consist of an α-subunit and a βγ-complex. In humans, interleukin 8 (IL-8) is one of most potent chemokine which binds to CXCR2. Expression of CD182 is found on several cell types including leukocytes, endothelial, and epithelial cells. CD182 plays a critical role in neutrophil homeostatis, angiogenesis, and in pathological conditions such as acute lung injury, lung diseases, and asthma. | Additional information: Clone REA208 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Belperio, J. A. et al. (2005) CXCR2/CXCR2 ligand biology during lung transplant ischemia-reperfusion injury. J Immunol 175: 6931–6939. | Thatcher, T. H. et al. (2005) Role of CXCR2 in cigarette smoke-induced lung inflammation. Am. J. Physiol. Lung Cell Mol. Physiol. 289: L322–L328.
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CD182 (CXCR2) Antibody, anti-human, APC, REAfinity™, 100 tests in 200 µL
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