- 询价
- Miltenyi Biotec
- 德国
- 130-126-529
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD16b
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA589
- 标记物：
FITC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
CD16b Antibody, anti-human, REAfinity™
- 抗体名：
CD16b Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of CD16b+ cells by flow cytometryClone REA589 recognizes the human CD16b antigen, a glycosylphosphatidylinositol-anchored protein known as low affinity immunoglobulin gamma Fc region receptor III-B. CD16 is expressed in two different isoforms, FcγRIIIa (CD16a), which is found on human NK cells, macrophages, and mast cells, and FcγRIIIb (CD16b) Fc receptors, that bind to the Fc portion of IgG antibodies which mediates NK cell activating. CD16b is polymorphic and has two codominant alleles that are related to Neutrophil Antigen 1 (NA1) and Neutrophil Antigen 2 (NA2). Clone REA589 is present on polymorphonuclear leukocytes (neutrophils) expressing the NA1 molecule. | Additional information: Clone REA589 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Ravetch, J. V. et al. (1989) Alternative membrane forms of Fc gamma RIII(CD16) on human natural killer cells and neutrophils. Cell type-specific expression of two genes that differ in single nucleotide substitutions. J. Exp. Med. 170 (2): 481–497. | Peltz, G. A. et al. (1989) Human Fc gamma RIII: cloning, expression, and identification of the chromosomal locus of two Fc receptors for IgG. Proc. Natl. Acad. Sci. U.S.A. 86 (3): 1013–1017. | Gessner, J. E. et al. (1995) The human low affinity immunoglobulin G Fc receptor III-A and III-B genes. Molecular characterization of the promoter regions. J. Biol. Chem. 270 (3): 1350–1361. | Monti, M. et al. (2017) Integrin-dependent cell adhesion to neutrophil extracellular traps through engagement of fibronectin in neutrophil-like cells. PLoS One 12 (2): .
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CD16b Antibody, anti-human, FITC, REAfinity™, 100 tests in 200 µL
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