- 询价
- Miltenyi Biotec
- 德国
- 130-139-042
- 2025年12月09日
- Flow cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD167a (DDR1)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA1391
- 标记物：
PE
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 抗体英文名：
CD167a (DDR1) Antibody, anti-human, REAfinity™
- 抗体名：
CD167a (DDR1) Antibody, anti-human, REAfinity™
- 规格：
30 tests in 60 µL
Identification and enumeration of CD167a (DDR1)+ cells by flow cytometryClone REA1391 recognizes the human CD167a (DDR1) antigen, a Single-pass type I membrane protein which is also known as Discoidin domain receptor (DDR1), Mammary carcinoma kinase 10 (MCK-10) or tyrosine kinase receptor E (trkE). CD167a (DDR1) is a tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. It promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. CD167a (DDR1) also plays a role in tumor cell invasion. Three isoforms of CD167a have been reported. It is expressed on epithelial cells, keratinocytes, leukocytes, monocytes and has been reported to be overexpressed in some breast carcinomas. | Additional information: Clone REA1391 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Di Marco, E. et al. (1993) Molecular cloning of trkE, a novel trk-related putative tyrosine kinase receptor isolated from normal human keratinocytes and widely expressed by normal human tissues. J. Biol. Chem. 268 (32): 2490–2495. | Canning, P. et al. (2014) Structural mechanisms determining inhibition of the collagen receptor DDR1 by selective and multi-targeted type II kinase inhibitors. J. Mol. Biol. 426 (13): 2457–2470. | Hohenester, E. (2014) Signalling complexes at the cell-matrix interface. Curr. Opin. Struct. Biol. 29C: 10–16.
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CD167a (DDR1) Antibody, anti-human, PE, REAfinity™, 30 tests in 60 µL
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