- 询价
- Miltenyi Biotec
- 德国
- 130-126-543
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Immunocytochemistry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD162
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA319
- 标记物：
FITC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Immunocytochemistry
- 浓度：
1:50
- 抗体英文名：
CD162 Antibody, anti-human, REAfinity™
- 抗体名：
CD162 Antibody, anti-human, REAfinity™
- 规格：
30 tests in 60 µL
Identification and enumeration of CD162+ cells by flow cytometryClone REA319 recognizes the human CD162 antigen, a single-pass type I membrane protein which is also known as P-selectin glycoprotein ligand 1 (PSGL-1). CD162 is expressed on neutrophils, monocytes, and most lymphocytes. It is the high affinity receptor for CD62P (P-selectin) on myeloid cells and stimulated T lymphocytes and mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. CD162 is also involved in homeostasis including stem cell homing to the thymus and mature T cell homing to secondary lymphoid organs. It has been found to bind the homeostatic chemokines CCL19 and CCL21 and to support the chemotactic response to these chemokines. | Additional information: Clone REA319 displays negligible binding to Fc receptors. | |
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文献和实验该产品被引用文献
Frenette, P. S. et al. (2000) P-selectin glycoprotein ligand 1 (PSGL-1) is expressed on platelets and can mediate platelet-endothelial interactions in vivo. J. Exp. Med. 191 (8): 1413–1422. | Sako, D. et al. (1993) Expression cloning of a functional glycoprotein ligand for P-selectin. Cell 75 (6): 1179–1186. | Carlow, D. A. et al. (2009) PSGL-1 function in immunity and steady state homeostasis. Immunol. Rev. 230 (1): 75–96. | Evani, S. J. et al. (2016) Biophysical regulation of Chlamydia pneumoniae-infected monocyte recruitment to atherosclerotic foci. Sci Rep 6: .
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CD162 Antibody, anti-human, FITC, REAfinity™, 30 tests in 60 µL
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