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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD161
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA227
- 标记物:
APC-Vio 770
- 适应物种:
rat
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:10
- 抗体英文名:
CD161 Antibody, anti-rat, REAfinity™
- 抗体名:
CD161 Antibody, anti-rat, REAfinity™
- 规格:
30 µg in 1 mL
Identification and enumeration of CD161+ cells by flow cytometryClone REA227 recognizes rat CD161, a C-type lectin membrane glycoprotein also known as NKR-P1. CD161 is expressed as an 80 kDa disulphide-linked homodimer and is found on most NK cells, T cell subsets, and many dendritic cells. In peripheral blood, CD161 is preferentially expressed on T cells of memory phenotype, but it can also be found on subsets of thymocytes and fetal liver T cells. CD161 has been implicated in triggering NK-mediated cytotoxicity, contributing to target cell recognition by NK cells. | Additional information: Clone REA227 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Giorda, R. et al. (1990) NKR-P1, a signal transduction molecule on natural killer cells. Science 249 (4974): 1298–1300. | Li, J. et al. (2003) Expression cloning and function of the rat NK activating and inhibitory receptors NKR-P1A and -P1B. Int. Immunol. 15 (3): 411–416.
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文献支持
CD161 Antibody, anti-rat, APC-Vio® 770, REAfinity™, 30 µg in 1 mL
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