- 询价
- Miltenyi Biotec
- 德国
- 130-121-347
- 2025年12月09日
- Flow cytometry, Mass cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD158b2 (KIR2DL3)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA147
- 标记物：
PE-Vio 770
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, Mass cytometry
- 浓度：
1:50
- 抗体英文名：
CD158b2 (KIR2DL3) Antibody, anti-human, REAfinity™
- 抗体名：
CD158b2 (KIR2DL3) Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of CD158b2 (KIR2DL3)+ cells by flow cytometryClone REA147 recognizes CD158b2, a killer cell immunoglobulin-like inhibitory receptor (KIR). Expressed by natural killer (NK) cells and a subset of T cells, KIR family of receptors are transmembrane glycoproteins and interact with MHC class I molecules. This interaction allows the KIR receptors to modulate the killing function of cells bearing them. The KIR proteins are categorized by the number of extracellular immunoglobulin domains (2D or 3D) and by the length (long (L) or short (S)) of the cytoplasmic domain. KIR proteins with the long cytoplasmic domain, such as CD158b2, transduce inhibitory signals via an immune tyrosine-based inhibitory motif (ITIM). | Additional information: Clone REA147 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Gendzekhadze, K. et al. (2009) Co-evolution of KIR2DL3 with HLA-C in a human population retaining minimal essential diversity of KIR and HLA class I ligands. Proc. Natl. Acad. Sci. U.S.A. 106: 18692–18697. | Keaney, L. et al. (2004) Investigation of killer cell immunoglobulin-like receptor gene diversity III. KIR2DL3. Tissue Antigens 64 (2): 188–194.
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CD158b2 (KIR2DL3) Antibody, anti-human, PE-Vio® 770, REAfinity™, 100 tests in 200 µL
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