- 询价
- Miltenyi Biotec
- 德国
- 130-106-916
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD157 (BST-1)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA465
- 标记物：
Biotin
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:11
- 抗体英文名：
CD157 (BST-1) Antibody, anti-human, REAfinity™
- 抗体名：
CD157 (BST-1) Antibody, anti-human, REAfinity™
- 规格：
100 tests in 1 mL
Identification and enumeration of CD157 (BST-1)+ cells by flow cytometryClone REA465 recognizes the human CD157 antigen, a glycosylphosphatidylinositol (GPI) linked protein, which is also known as bone marrow stromal antigen 1 (BST-1) or cyclic ADP-ribose hydrolase 2. CD157, a member of the CD38 gene family, is an NAD-metabolizing ectoenzyme and a signaling molecule, which synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, former a second messenger that elicits calcium release from intracellular stores. It is mainly expressed by cells of the myeloid lineage, bone marrow stroma, and vascular endothelium. CD157 is also expressed by ovarian cancer epithelium and by peritoneal mesothelial cells, where it is implicated in tumor dissemination. Further, it is endowed with receptor-like features observed in different cell types and transduces signals by interacting with transmembrane partner molecules, a strategy shared by other GPI-anchored molecules. CD157 is involved in neutrophil polarization, adhesion, and motility and controls transendothelial migration. | Additional information: Clone REA465 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Kaisho, T. et al. (1994) BST-1, a surface molecule of bone marrow stromal cell lines that facilitates pre-B-cell growth. Proc. Natl. Acad. Sci. U.S.A. 91 (12): 5325–5329. | Ishihara, K. et al. (2000) BST-1/CD157 regulates the humoral immune responses in vivo. Chem. Immunol. 75: 235–255. | Morone, S. et al. (2014) Binding of CD157 protein to fibronectin regulates cell adhesion and spreading. J. Biol. Chem. 289 (22): 15588–15601.
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CD157 (BST-1) Antibody, anti-human, Biotin, REAfinity™, 100 tests in 1 mL
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