文献支持
CD156c (ADAM10) Antibody, anti
-human, PerCP-Vio® 700, REAfinity™, 100 tests in 200 µL- 询价
- Miltenyi Biotec
- 德国
- 130-130-001
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD156c (ADAM10)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA309
- 标记物：
PerCP-Vio 700
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
CD156c (ADAM10) Antibody, anti-human, REAfinity™
- 抗体名：
CD156c (ADAM10) Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of CD156c (ADAM10)+ cells by flow cytometryClone REA309 recognizes the human CD156c antigen, a single-pass type I membrane protein which is also known as disintegrin or metalloproteinase domain-containing protein 10 (ADAM10). CD156c belongs to the family of disintegrin and metalloproteinases (ADAMs) and is expressed ubiquitously on hematopoietic and non-hematopoietic cells. ADAMs have emerged as the major proteinase family that mediates proteolytic ectodomain release, a process known as shedding. This shedding process has been recognised as a key mechanism for regulating the function of a diversity of cell surface proteins. Dysregulation of ectodomain shedding is associated with autoimmune and cardiovascular diseases, neurodegeneration, infection, inflammation, and cancer. CD156c has been studied in the context of ectodomain shedding and has been demonstrated as key molecule in most of the shedding events in cancer and neurodegenerative disorders. | Additional information: Clone REA309 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Weber, C. et al. (2013) Regulation of adult hematopoiesis by the a disintegrin and metalloproteinase 10 (ADAM10). Biochem. Biophys. Res. Commun. 442 (3-4): 234–241. | Moss, M. L. and Bartsch, J. W. (2004) Therapeutic benefits from targeting of ADAM family members. Biochem. J. 43 (23): 7227–7235. | Rosendahl, M. S. et al. (1997) Identification and characterization of a pro-tumor necrosis factor-alpha-processing enzyme from the ADAM family of zinc metalloproteases. J. Biol. Chem. 272 (39): 24588–24593.
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CD156c (ADAM10) Antibody, anti-human, PerCP-Vio® 700, REAfinity™, 100 tests in 200 µL
询价
