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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD158e/k (KIR3DL1/DL2)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA970
- 标记物:
PE
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, Mass cytometry
- 浓度:
1:50
- 抗体英文名:
CD158e/k (KIR3DL1/DL2) Antibody, anti-human, REAfinity™
- 抗体名:
CD158e/k (KIR3DL1/DL2) Antibody, anti-human, REAfinity™
- 规格:
30 tests in 60 µL
Identification and enumeration of CD158e/k (KIR3DL1/DL2)+ cells by flow cytometryClone REA970 recognizes the human CD158e (KIR3DL1) and CD158k (KIR3DL2) antigens, members of the killer immunoglobulin-like receptor (KIR) family which recognizes subsets of HLA alleles. The family of KIR contributes to the regulation of NK cell–mediated cytotoxicity. Expression is found mainly on CD56dimCD16+ natural killer (NK) cells but also on a subset of CD8+ T cells. They are monomeric receptors possessing high allelic polymorphism with either two or three Ig-like extracellular domains. According to the length of their cytoplasmic tail, KIRs can be subdivided in inhibitory KIRs and activating KIRs. | Additional information: Clone REA970 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Yawata, M. et al. (2002) Variation within the human killer cell immunoglobulin-like receptor (KIR) gene family. Crit. Rev. Immunol. 22 (5–6): 463–482. | Uhrberg, M. (2005) The KIR gene family: life in the fast lane of evolution. Eur. J. Immunol. 35 (1): 10–15.
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CD158e/k (KIR3DL1/DL2) Antibody, anti-human, PE, REAfinity™, 30 tests in 60 µL
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