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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD156a (ADAM8)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA331
- 标记物:
PE
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:11
- 抗体英文名:
CD156a (ADAM8) Antibody, anti-human, REAfinity™
- 抗体名:
CD156a (ADAM8) Antibody, anti-human, REAfinity™
- 规格:
100 tests in 1 mL
Identification and enumeration of CD156a (ADAM8)+ cells by flow cytometryClone REA331 recognizes the human CD156a antigen, a single-pass type I transmembrane protein which is also known as disintegrin or metalloproteinase domain-containing protein 8 (ADAM8). The ADAM family members are membrane-anchored proteins with wide ranging functions, including proteolytic cleavage of cell surface molecules, cell fusion, cell adhesion, and intracellular signaling. CD156a is expressed mainly in cells of the immune system, such as monocytes, neutrophils, eosinophils, dendritic cells, and B cells. As for most ADAM family members, CD156a is involved in ectodomain shedding of membrane proteins like CD23 and L-selectin and is linked to allergic inflammation and neurodegeneration. | Additional information: Clone REA331 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Koller, G. et al. (2009) ADAM8/MS2/CD156, an emerging drug target in the treatment of inflammatory and invasive pathologies. Curr. Pharm. Des. 15 (20): 2272–2281. | Yoshiyama, K. et al. (1997) CD156 (human ADAM8): expression, primary amino acid sequence, and gene location. Genomics 41 (1): 56–62. | Matsuno, O. et al. (2008) ADAM8 in allergy. Inflamm. Allergy Drug Targets 7 (2): 108–112.
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CD156a (ADAM8) Antibody, anti-human, PE, REAfinity™, 100 tests in 1 mL
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