- 询价
- Miltenyi Biotec
- 德国
- 130-119-179
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD155
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA1081
- 标记物：
APC-Vio 770
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
CD155 Antibody, anti-human, REAfinity™
- 抗体名：
CD155 Antibody, anti-human, REAfinity™
- 规格：
30 tests in 60 µL
Identification and enumeration of CD155+ cells by flow cytometryClone REA1081 recognizes the human CD155 antigen, a single-pass type I membrane protein also known as poliovirus receptor (PVR) or nectin-like protein 5 (NECL-5). CD155 is composed of two Ig-like C2-type domains and one Ig-like V-type domain that is necessary for poliovirus binding and uptake. Four different isotypes (α to δ) exist, originated from alternate splicing of the CD155 mRNA. CD155 is a broadly expressed receptor which is found on, for example, monocytes, a T cell subset, and neurons of the central nervous system. CD155 is also expressed on some CD34+ progenitor cells, particulary on progenitors committed in myeloid differentiation. It can interact with several ligands, such as CD226, TIGIT, CD96, vitronectin, integrin αvβ3, and PDGFR. The functions of CD155 include roles in cell adhesion, neural differentiation, and NK cell effector functions. | Additional information: Clone REA1081 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Mendelsohn, C. L. et al. (1989) Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily. Cell 56 (5): 855 –865. | Lozano, E. et al. (2013) The CD226/CD155 interaction regulates the proinflammatory (Tʜ1/Tʜ17)/anti-inflammatory (Tʜ2) balance in humans. J Immunol 191 (7): 3673–3680.
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CD155 Antibody, anti-human, APC-Vio® 770, REAfinity™, 30 tests in 60 µL
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