- 询价
- Miltenyi Biotec
- 德国
- 130-100-722
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD144 (VE-Cadherin)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA199
- 标记物：
PE-Vio 770
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:11
- 抗体英文名：
CD144 (VE-Cadherin) Antibody, anti-human, REAfinity™
- 抗体名：
CD144 (VE-Cadherin) Antibody, anti-human, REAfinity™
- 规格：
100 tests in 1 mL
Identification and enumeration of CD144 (VE-Cadherin)+ cells by flow cytometryClone REA199 recognizes CD144 (VE-Cadherin), a 120 KDa type II cadherin. Cadherins are cell adhesion molecules and mediate Ca 2)+ dependent homophilic interactions. CD144 contains five extracellular cadherin (EC) domains and like other cadherins can interact directly via its C-terminus with cytoplasmic proteins such as β-catenin, plaktoglobin, and p120. Plaktoglobin und β-catenin bind to α-catenin, which in turn interacts with several actin-binding proteins, α-actinin, ajuba, zonula occludens-1 (ZO-1). Further indirect interactions of CD144 with partners such as SHP-2, VEGFR-2, Csk, and PAR-3, 6 allows CD144 to not only regulate the stability and strength of cell adhesion but also to serve functions such as sensing of shear forces, anti-proliferative, and anti-apoptotic effects. | Additional information: Clone REA199 displays negligible binding to Fc receptors. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验该产品被引用文献
Vincent, P. A. et al. (2004) VE-cadherin: adhesion at arm's length. Am. J. Physiol., Cell Physiol. 286: C987–C997. | Nelson, C. M. and Chen, C. S. (2003) VE-cadherin simultaneously stimulates and inhibits cell proliferation by altering cytoskeletal structure and tension. J. Cell. Sci. 116: 3571–3581. | Odell, A. F. et al. (2012) A VE-cadherin–PAR3–α-catenin complex regulates the Golgi localization and activity of cytosolic phospholipase A2α in endothelial cells. Mol. Biol. Cell 23: 1783–1796.
技术资料暂无技术资料 索取技术资料
文献支持
CD144 (VE-Cadherin) Antibody, anti-human, PE-Vio® 770, REAfinity™, 100 tests in 1 mL
询价
