- 询价
- Miltenyi Biotec
- 德国
- 130-116-092
- 2025年12月09日
- Flow cytometry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD141 (BDCA-3)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA964
- 标记物：
Biotin
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 抗体英文名：
CD141 (BDCA-3) Antibody, anti-mouse, REAfinity™
- 抗体名：
CD141 (BDCA-3) Antibody, anti-mouse, REAfinity™
- 规格：
30 µg in 200 µL
Identification and enumeration of CD141 (BDCA-3)+ cells by flow cytometryClone REA964 recognizes the mouse CD141 antigen, which is also known as BDCA-3, thrombomodulin, or fetomodulin. CD141 is a type I cell surface glycoprotein expressed mainly on endothelial cells. CD141 functions as a specific endothelial cell receptor for thrombin. This complex cleaves protein C and the thrombin activatable fibrinolysis Inhibitor (TAFI), initiating an anticoagulant pathway. | Additional information: Clone REA964 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Dittman, W. A. et al. (1988) The structure and function of mouse thrombomodulin. Phorbol myristate acetate stimulates degradation and synthesis of thrombomodulin without affecting mRNA levels in hemangioma cells. J. Biol. Chem. 263 (30): 15815–15822. | Bajzar, L. et al. (1996) TAFI, or plasma procarboxypeptidase B, couples the coagulation and fibrinolytic cascades through the thrombin-thrombomodulin complex. J. Biol. Chem. 271 (28): 16603–16608. | Isermann, B. et al. (2001) Endothelium-specific loss of murine thrombomodulin disrupts the protein C anticoagulant pathway and causes juvenile-onset thrombosis. J. Clin. Invest. 108 (4): 537–546.
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CD141 (BDCA-3) Antibody, anti-mouse, Biotin, REAfinity™, 30 µg in 200 µL
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