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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD140b
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA634
- 标记物:
Biotin
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
CD140b Antibody, anti-mouse, REAfinity™
- 抗体名:
CD140b Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 200 µL
Identification and enumeration of CD140b+ cells by flow cytometryClone REA634 recognizes the mouse CD140b antigen, also known as platelet-derived growth factor receptor-β (PDGFR-β), a tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB. CD140b plays a role in the regulation of embryonic development, cell proliferation, differentiation, chemotaxis, survival, and migration. CD140b is expressed on embryonic tissues and mesenchymal-derived cells in adult mice. | Additional information: Clone REA634 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Seifert, R. A. et al. (1993) PDGF-AB requires PDGF receptor alpha-subunits for high-affinity, but not for low-affinity, binding and signal transduction. J. Biol. Chem. 268 (6): 4473–4480. | Tallquist, M. D. et al. (2003) Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development. PLoS Biol. 1 (2): E52. | Taneda, S. et al. (2003) Obstructive uropathy in mice and humans: potential role for PDGF-D in the progression of tubulointerstitial injury. J. Am. Soc. Nephrol. 14 (10): 2544–2555.
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CD140b Antibody, anti-mouse, Biotin, REAfinity™, 30 µg in 200 µL
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