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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD138
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA104
- 标记物:
PE
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
CD138 Antibody, anti-mouse, REAfinity™
- 抗体名:
CD138 Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 200 µL
Identification and enumeration of CD138+ cells by flow cytometryCD138, also known as syndecan-1, is a type I integral membrane protein belonging to the syndecan protein family which carries three to five heparan sulfate and chondroitin sulfate chains. CD138 is highly expressed on plasma cells and pre–B cells but not on mature peripheral B cells. It is also expressed on fibroblasts and epithelial cells. The expression of CD138 can be regulated by several cytokines and factors, e.g., thrombin, which is reported to increase the synthesis of CD138 molecules that exhibit high-affinity antithrombin-3 binding. | Additional information: Clone REA104 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Cizmeci-Smith, G. et al. (1997) Thrombin stimulates Syndecan-1 promotor activity and expression of a form of Syndecan-1 that binds antithrombin III in vascular smooth muscle cells. Arterioscler. Thromb. Vasc. Biol. 17: 2609 –2616. | Sanderson, R. D. et al. (1989) B lymphocytes express and lose syndecan at specific stages of differentiation. Cell Regul. 1 (1): 27–35. | Jalkanen, M. et al. (1985) Heparan sulfate proteoglycans from mouse mammary epithelial cells: localization on the cell surface with a monoclonal antibody. J. Cell Biol. 101 (3): 976–984. | Saunders, S. et al. (1989) Molecular cloning of syndecan, an integral membrane proteoglycan. J. Cell Biol. 108 (4): 1547–1556. | Chilosi, M. et al. (1999) CD138/syndecan-1: a useful immunohistochemical marker of normal and neoplastic plasma cells on routine trephine bone marrow biopsies. Mod. Pathol. 12 (12): 1101–1106.
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CD138 Antibody, anti-mouse, PE, REAfinity™, 30 µg in 200 µL
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