- 询价
- Miltenyi Biotec
- 德国
- 130-130-426
- 2025年12月09日
- Flow cytometry
- human cell line
- rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD134 (OX40)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA540
- 标记物：
PE-Vio 770
- 适应物种：
rat
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 抗体英文名：
CD134 (OX40) Antibody, anti-rat, REAfinity™
- 抗体名：
CD134 (OX40) Antibody, anti-rat, REAfinity™
- 规格：
30 µg in 200 µL
Identification and enumeration of CD134 (OX40)+ cells by flow cytometryClone REA540 recognizes the rat CD134 (OX40) antigen, a 50 kDa glycoprotein which is a member of the TNFR superfamily. It contains a typical signal sequence and a single putative transmembrane sequence of 25 predominantly hydrophobic amino acids giving an extracellular domain of 191 amino acids and a cytoplasmic domain of 36 amino acids. The expression of CD134 is restricted to activated rat CD4+ T cells and is up-regulated within hours after activation. CD134 and its ligand CD252 (CD134L, OX40L), which is expressed on activated T and B lymphocytes and also a member of the tumor necrosis factor receptor superfamily, were suggested to mediate the interaction between T cells and B cells. | Additional information: Clone REA540 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Calderhead, D. M. et al. (1993) Cloning of mouse Ox40: a T cell activation marker that may mediate T-B cell interactions. J Immunol 151: 5261–5271. | Mallett, S. et al. (1990) Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes--a molecule related to nerve growth factor receptor. EMBO J. 9 (4): 1063–1068. | Al-Shamkhanie, A. et al. (1997) Affinity and kinetics of the interaction between soluble trimeric OX40 ligand, a member of the tumor necrosis factor superfamily, and its receptor OX40 on activated T cells. J. Biol. Chem. 272: 5275–5282.
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CD134 (OX40) Antibody, anti-rat, PE-Vio® 770, REAfinity™, 30 µg in 200 µL
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