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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD131
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA249
- 标记物:
APC
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:11
- 抗体英文名:
CD131 Antibody, anti-human, REAfinity™
- 抗体名:
CD131 Antibody, anti-human, REAfinity™
- 规格:
30 tests in 300 µL
Identification and enumeration of CD131+ cells by flow cytometryClone REA249 recognizes the human CD131 antigen, a type I transmembrane glycoprotein also known as IL-3R common subunit β or GM-CSF/IL-3/IL-5 receptor common β chain. CD131 forms heterodimers with the α subunit of the receptor complexes for human granulocyte-macrophage colony stimulating factor (GM-CSFR), interleukin 3 (IL-3R), and interleukin 5 (IL-5R). These cytokine receptors are expressed by several different cell types like neutrophils, eosinophils, monocytes, endothelial cells, fibroblasts, and hematopoietic progenitor cells. | Additional information: Clone REA249 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Rossjohn, J. et al. (2000) Structure of the activation domain of the GM-CSF/IL-3/IL-5 receptor common beta-chain bound to an antagonist. Blood 95 (8): 2491–2498. | Hansen, G. et al. (2008) The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation. Cell 134 (3): 496–507.
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CD131 Antibody, anti-human, APC, REAfinity™, 30 tests in 300 µL
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