- 询价
- Miltenyi Biotec
- 德国
- 130-114-115
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD11c
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA618
- 标记物：
Vio Bright FITC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry
- 浓度：
1:50
- 抗体英文名：
CD11c Antibody, anti-human, REAfinity™
- 抗体名：
CD11c Antibody, anti-human, REAfinity™
- 规格：
30 tests in 60 µL
Identification and enumeration of CD11c+ cells by flow cytometryClone REA618 recognizes the human CD11c antigen, a 145–150 kDa type I transmembrane glycoprotein, which is also known as integrin αX or CR4. It is expressed on monocytes, macrophages, NK cells, granulocytes, myeloid dendritic cells (MDCs), and subsets of T and B cells. On myeloid dendritic cells, CD11c is highly expressed on type 1 myeloid dendritic cells (CD1c (BDCA-1)+ CD123low MDC1s) and low on type 2 myeloid dendritic cells (CD1c (BDCA-1)– CD123– MDC2s). CD11c, also known as integrin integrin αX or CR4, has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b. | Additional information: Clone REA618 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Dzionek, A. et al. (2000) BDCA-2, BDCA-3, BDCA-4: Three markers for distinct subsets of dendritic cells in human peripheral blood. J Immunol 165: 6037–6046. | Bendiss-Vermare, N. et al. (2001) Human thymus contains IFN-alpha-producing CD11c–, myeloid CD11c+, and mature interdigitating dendritic cells. J. Clin. Invest. 107: 835–844. | Barclay, A. N. et al. (1997) In: The Leukocyte Antigen Facts Book, Academic Press, San Diego, CA. (2nd edition): 161–162.
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CD11c Antibody, anti-human, Vio® Bright FITC, REAfinity™, 30 tests in 60 µL
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