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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD11b
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA713
- 标记物:
PE-Vio 770
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, Mass cytometry
- 浓度:
1:50
- 抗体英文名:
CD11b Antibody, anti-human, REAfinity™
- 抗体名:
CD11b Antibody, anti-human, REAfinity™
- 规格:
100 tests in 200 µL
Identification and enumeration of CD11b+ cells by flow cytometryClone REA713 recognizes the human CD11b antigen (Mac-1 α; integrin αM chain), which is part of the CD11b/CD18 heterodimer (Mac-1 α, Mβ2 integrin), also known as the C3 complement receptor. It functions as a receptor for complement (C3bi), fibrinogen, or clotting factor X. In humans, CD11b is strongly expressed on myeloid cells and weakly expressed on natural killer (NK) cells and some activated lymphocytes as well as on microglia in the brain. | Additional information: Clone REA713 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Pahl, H. L. et al. (1992) Characterization of the myeloid-specific CD11b promoter. Blood 79 (4): 865–870. | Lebson, L. et al. (2010) Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice. J. Neurosci. 30 (29): 9651–9658. | Liu, T. et al. (2014) Gr-1+CD11b+ cells facilitate Lewis lung cancer recurrence by enhancing neovasculature after local irradiation. Sci Rep 4: 4833.
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CD11b Antibody, anti-human, PE-Vio® 770, REAfinity™, 100 tests in 200 µL
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