- 询价
- Miltenyi Biotec
- 德国
- 130-116-892
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD122 (IL-2Rβ)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA1015
- 标记物：
PE-Vio 615
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
CD122 (IL-2Rβ) Antibody, anti-mouse, REAfinity™
- 抗体名：
CD122 (IL-2Rβ) Antibody, anti-mouse, REAfinity™
- 规格：
150 µg in 1 mL
Identification and enumeration of CD122 (IL-2Rβ)+ cells by flow cytometryClone REA1015 recognizes the murine CD122 70–75 kDa cell surface glycoprotein, also known as interleukin-2 receptor beta chain (IL-2Rβ). CD122 is constitutively expressed on mouse NK cells and at a lower level on subsets of T cells, B cells, monocytes, and macrophages. CD122 can associate with the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25), resulting in intermediate or high affinity IL-2 receptor complexes. CD122 expression levels can be upregulated by activation. Clone REA1015 interferes with binding of IL-2 to the receptor and can be used to deplete CD122+ cells. | Additional information: Clone REA1015 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Tanaka, T. et al. (1991) A novel monoclonal antibody against murine IL-2 receptor beta-chain. Characterization of receptor expression in normal lymphoid cells and EL- 4 cells. J Immunol 147: 2222–2228. | Tang, Y. et al. (2011) Emergence of NK cell progenitors and functionally competent NK cell lineage subsets in the early mouse embryo. Blood 120: 63–75. | Malek, T. R. et al. (1995) Biochemical identity and characterization of the mouse interleukin-2 receptor beta and gamma c subunits. J. Interferon Cytokine Res. 15 (5): 447–454. | Nishikawa, Y. et al. (2010) Roles of CD122+ cells in resistance against Neospora caninum infection in a murine model. J. Vet. Med. Sci. 72 (10): 1275–1282.
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CD122 (IL-2Rβ) Antibody, anti-mouse, PE-Vio® 615, REAfinity™, 150 µg in 1 mL
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