- 询价
- Miltenyi Biotec
- 德国
- 130-100-255
- 2025年12月09日
- Flow cytometry, Mass cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD122 (IL-2Rβ)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA167
- 标记物：
PE
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, Mass cytometry
- 浓度：
1:11
- 抗体英文名：
CD122 (IL-2Rβ) Antibody, anti-human, REAfinity™
- 抗体名：
CD122 (IL-2Rβ) Antibody, anti-human, REAfinity™
- 规格：
30 tests in 300 µL
Identification and enumeration of CD122 (IL-2Rβ)+ cells by flow cytometryClone REA167 recognizes CD122, the 75 KDa β subunit of the high and intermediate affinity interleukin 2 receptor (IL-2R). CD122 is a type I transmembrane protein, and together with α subunit (CD25) or with α and γ (CD132) subunit, it forms the heteromeric intermediate and high affinity IL-2 receptors, respectively. In addition, CD122 is also a component of the IL-15 receptor complex. Expression of CD122 is found constitutively in CD8 cytotoxic T cells but not in CD4 Tʜ cells and is further induced upon T cell activation. CD16+ NK lymphocytes also express CD122 constitutively. CD122 is essential for IL-2 signaling. | Additional information: Clone REA167 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Gesbert, F. et al. (2005) IL-2 responsiveness of CD4 and CD8 lymphocytes: further investigations with human IL-2Rß transgenic mice. Int. Immunol. 17: 1093–1102. | Friedmann, M. C. et al. (1996) Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation. Proc. Natl. Acad. Sci. U.S.A. 93 (5): 2077–2082. | Migone, T. S. et al. (1998) Functional cooperation of the interleukin-2 receptor beta chain and Jak1 in phosphatidylinositol 3-kinase recruitment and phosphorylation. Mol. Cell. Biol. 18 (11): 6416–6422.
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CD122 (IL-2Rβ) Antibody, anti-human, PE, REAfinity™, 30 tests in 300 µL
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