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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD11a/CD18
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA880
- 标记物:
APC
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
CD11a/CD18 Antibody, anti-mouse, REAfinity™
- 抗体名:
CD11a/CD18 Antibody, anti-mouse, REAfinity™
- 规格:
150 µg in 1 mL
Identification and enumeration of CD11a/CD18+ cells by flow cytometryClone REA 880 recognizes the CD11a/CD18 heterodimer, also known as lymphocyte function–associated antigen 1 (LFA-1). LFA-1 is a member of the integrin family and consists of two chains, a (CD11a) and b2 (CD18). It is expressed on T and B cells as well as on macrophages and neutrophils. LFA-1 plays an essential role in the immune system, e.g., in leukocyte adhesion by interaction with ICAM-1 and ICAM-2, in cytotoxic T cell–mediated killing, antibody-dependent killing by granulocytes and monocytes, and in T cell proliferation. | Additional information: Clone REA880 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Kaufmann, Y. et al. (1991) Cloning of the murine lymphocyte function-associated molecule-1 alpha-subunit and its expression in COS cells. J Immunol 147 (1): 369–374. | Lub, M. et al. (1995) Ins and outs of LFA-1. Immunol. Today 16 (10): 479–483. | Liu, Z. et al. (2006) Differential roles for beta2 integrins in experimental autoimmune bullous pemphigoid. Blood 107 (3): 1063–1069. | Liu, Y. et al. (2011) Expression of p16INK4a prevents cancer and promotes aging in lymphocytes. Blood 117: 3257–3267.
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CD11a/CD18 Antibody, anti-mouse, APC, REAfinity™, 150 µg in 1 mL
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