- 询价
- Miltenyi Biotec
- 德国
- 130-119-184
- 2025年12月09日
- Flow cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD114
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA1082
- 标记物：
APC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 抗体英文名：
CD114 Antibody, anti-human, REAfinity™
- 抗体名：
CD114 Antibody, anti-human, REAfinity™
- 规格：
30 tests in 60 µL
Identification and enumeration of CD114+ cells by flow cytometryClone REA1082 recognizes the receptor for granulocyte colony stimulating factor (G-CSFR, CSF3) a 130–150 kDa type I transmembrane glycoprotein of the class 1 cytokine receptor gene family also known as CD114. Ligand binding leads to homodimerization and subsequent signal transduction involving the JAK-STAT pathway. CD114 is expressed by neutrophils at all stages of differentiation but also found on monocytes, endothelial cells, mature platelets, trophoblasts, and placenta. | Additional information: Clone REA1082 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Ward, A. C. (2007) The role of the granulocyte colony-stimulating factor receptor (G-CSF-R) in disease. Front Biosci. 12: 608–618. | Liongue, C. et al. (2009) Granulocyte colony-stimulating factor receptor: stimulating granulopoiesis and much more. Int. J. Biochem. Cell Biol. 12 (41): 2372–2375. | Piper, M. G. et al. (2010) Neutrophil elastase downmodulates native GCSFR expression and granulocyte-macrophage colony formation. J. Inflamm. 7 (1): 5. | Gibbs, K. D. et al. (2011) Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments. Blood 117: 4226–4233.
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CD114 Antibody, anti-human, APC, REAfinity™, 30 tests in 60 µL
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