- 询价
- Miltenyi Biotec
- 德国
- 130-123-984
- 2025年12月09日
- Flow cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD110
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA250
- 标记物：
PE
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 抗体英文名：
CD110 Antibody, anti-human, REAfinity™
- 抗体名：
CD110 Antibody, anti-human, REAfinity™
- 规格：
30 tests in 60 µL
Identification and enumeration of CD110+ cells by flow cytometryClone REA250 recognizes the CD110 antigen, a type I transmembrane protein and a member of the hematopoietin receptor family, which is also known as myeloproliferative leukemia protein (MPL) or thrombopoietin receptor (TPO-R). CD110 is expressed on hematopoietic stem cells, a subfraction of hematopoietic precursor cells, cells of the megakaryocytic lineage, and platelets. It serves as a receptor for thrombopoietin and CD110 deficiency leads to severe thrombocytopenia, emphasizing the important role of CD110 and thrombopoietin in megakaryocyte and platelet formation. | Additional information: Clone REA250 displays negligible binding to Fc receptors. | |
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文献和实验该产品被引用文献
Vigon, I. et al. (1992) Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily. Proc. Natl. Acad. Sci. U.S.A. 89: 5640 –5644. | Chou, F. S. et al. (2011) The thrombopoietin/MPL pathway in hematopoiesis and leukemogenesis. J. Cell. Biochem. 112 (6): 1491–1498. | Kaushansky, K. et al. (1998) The role of the MPL receptor in myeloproliferative disorders. Leukemia 12: S47–S50.
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CD110 Antibody, anti-human, PE, REAfinity™, 30 tests in 60 µL
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