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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD108 (SEMA7A)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA1467
- 标记物:
APC
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 抗体英文名:
CD108 (SEMA7A) Antibody, anti-human, REAfinity™
- 抗体名:
CD108 (SEMA7A) Antibody, anti-human, REAfinity™
- 规格:
100 tests in 200 µL
Identification and enumeration of CD108 (SEMA7A)+ cells by flow cytometryClone REA1467 recognizes the CD108 (SEMA7A) antigen, an 80-kD glycoprotein expressed on some leukemic cell lines, activated lymphocytes and erythrocytes. Its surface expression is rapidly upregulated if it is stimulated with PHA, PWM, Con A, PMA or anti-CD3 and subsequently gradually decreases. SEMA7A is expressed in various adult tissues such as adipose, colon, esophagus, heart, brain, spleen, testis, lung, ovary, and uterus. CD108 is important for integrin-mediated signaling and functions in regulating cell migration and immune responses and plays an important role in modulating inflammation and T-cell-mediated immune responses. | Additional information: Clone REA1467 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Angelisová , P. et al. (1999) Characterization of the human leukocyte GPI-anchored glycoprotein CDw108 and its relation to other similar molecules. Immunobiology 200 (2): 234–245. | Suzuki, K. et al. Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin. Nature 446 (7136): 680–684. | Yang, L. et al. (2024) Pan-Cancer Analysis of the Prognostic and Immunological Role of SEMA7A. Int J Gen Med. 17: 6443 doi–6461.
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CD108 (SEMA7A) Antibody, anti-human, APC, REAfinity™, 100 tests in 200 µL
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