- 询价
- Miltenyi Biotec
- 德国
- 130-115-834
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD101
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA954
- 标记物：
Vio Bright B515
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
CD101 Antibody, anti-human, REAfinity™
- 抗体名：
CD101 Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of CD101+ cells by flow cytometryClone REA954 recognizes the human CD101 antigen, also known as V7 or IGSF2, which is a 140 kDa type I transmembrane glycoprotein of the Ig gene superfamily. CD101 is expressed on monocytes, granulocytes, and subsets of dendritic cells (DCs). In addition, CD101 is expressed on certain subpopulations of T cells, in particular about 5–30% of FoxP3+ Treg cells in peripheral blood. The interaction of CD101 with clone REA954 has been shown to inhibit T cell activation by allogeneic DCs or CD3 antibodies. | Additional information: Clone REA954 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Rivas, A. et al. (1995) V7, a novel leukocyte surface protein that participates in T cell activation. J Immunol 154: 4423–4433. | Soares, L. R. et al. (1998) V7 (CD101) ligation inhibits TCR/CD3-induced IL-2 production by blocking Ca2+ flux and nuclear factor of activated T cell nucleartranslocation. J Immunol 161: 209–217. | Bouloc, A. et al. (2000) Triggering CD101 molecule on human cutaneous dendritic cells inhibits T cell proliferation via IL-10 production. Eur. J. Immunol. 30: 3132–3139.
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CD101 Antibody, anti-human, Vio® Bright B515, REAfinity™, 100 tests in 200 µL
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