- 询价
- Miltenyi Biotec
- 德国
- 130-104-762
- 2025年12月09日
- Flow cytometry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD100
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA322
- 标记物：
FITC
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:10
- 抗体英文名：
CD100 Antibody, anti-mouse, REAfinity™
- 抗体名：
CD100 Antibody, anti-mouse, REAfinity™
- 规格：
9 µg in 300 µL
Identification and enumeration of CD100+ cells by flow cytometryClone REA322 recognizes the mouse CD100 antigen, a single-pass type I membrane protein which is also known as semaphorin 4D (Sema4D). CD100 is strongly expressed in lymphoid tissues, especially in the thymus, as well as in the nervous tissues. It is also overexpressed by some malignancies and plays a role in tumor-induced angiogenesis similar to vascular endothelial growth factor. CD100 is a member of a family of transmembrane and secreted proteins that have been shown to act through its receptor plexin-B1 to regulate axon growth cone guidance, lymphocyte activation, and bone density. It has been shown to interact with the B cell coreceptor CD72 for enhancing B cell receptor signaling. | | Additional information: Clone REA322 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Furuyama, T. et al. (1996) Identification of a novel transmembrane semaphorin expressed on lymphocytes. J. Biol. Chem. 271 (52): 33376–33381. | Lu, L. et al. (2014) Changes of temporomandibular joint and semaphorin 4D/plexin-B1 expression in a mouse model of incisor malocclusion. J Oral Facial Pain Headache 28 (1): 68–79. | Zhou, H. et al. (2014) The Semaphorin 4D-Plexin-B1-RhoA signaling axis recruits pericytes and regulates vascular permeability through endothelial production of PDGF-B and ANGPTL4. Angiogenesis 17 (1): 261–274.
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CD100 Antibody, anti-mouse, FITC, REAfinity™, 9 µg in 300 µL
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