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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD105
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA1058
- 标记物:
Vio Bright B515
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
CD105 Antibody, anti-mouse, REAfinity™
- 抗体名:
CD105 Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 200 µL
Identification and enumeration of CD105+ cells by flow cytometryClone REA1058 recognizes the mouse CD105 antigen, also known as endoglin. CD105 is a proliferation-associated and hypoxia-inducible protein, abundantly expressed in angiogenic endothelial cells. In mouse bone marrow, CD105 is also expressed on a population of Sca-1+ hematopoietic stem cells (HSCs). This population has a long-term repopulating (LTR) capacity and is therefore termed LTR-HSCs. Furthermore, on liver sinusoidal endothelial cells (LSEC), CD105 is co-expressed with CD146 (LSEC). | Additional information: Clone REA1058 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Chen, C. Z. et al. (2002) Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cells. Proc. Natl. Acad. Sci. U.S.A. 99: 15468–15473. | Chen, C. Z. et al. (2003) The endoglin(positive) sca-1(positive) rhodamine(low) phenotype defines a near-homogeneous population of long-term repopulating hematopoietic stem cells. Immunity 19: 525–533.
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CD105 Antibody, anti-mouse, Vio® Bright B515, REAfinity™, 30 µg in 200 µL
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