- 询价
- Miltenyi Biotec
- 德国
- 130-106-924
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD104 (Integrin β4)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA456
- 标记物：
APC
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:10
- 抗体英文名：
CD104 (Integrin β4) Antibody, anti-mouse, REAfinity™
- 抗体名：
CD104 (Integrin β4) Antibody, anti-mouse, REAfinity™
- 规格：
30 µg in 1 mL
Identification and enumeration of CD104 (Integrin β4)+ cells by flow cytometryClone REA456 recognizes the mouse CD104 antigen, a single-pass type I membrane protein which is also known as integrin β4 (Itgb4). Integrins are a family of heterodimeric glycoprotein receptors and exist as non-covalently bound α and β subunits. CD104 interacts with α6 integrin and serves as receptor for laminin and component of hemidesmosomes. Expression of α6β4 integrin is found in the basal aspect of stratified epithelia such as epidermis, stratified squamous epithelium of squamous mucosa, urotheliumin, and certain tumor cells. CD104 is likely to play a pivotal role in the biology of invasive carcinoma. | Additional information: Clone REA456 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Murgia, C. et al. (1998) Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin beta4 cytoplasmic domain. EMBO J. 17 (14): 3940–3951. | Pal-Ghosh, S. et al. (2011) MMP9 cleavage of the β4 integrin ectodomain leads to recurrent epithelial erosions in mice. J. Cell. Sci. 124 (Pt 15): 2666–2675. | Simon-Assmann, P. et al. (1994) Differential expression of laminin isoforms and alpha 6-beta 4 integrin subunits in the developing human and mouse intestine. Dev. Dyn. 201 (1): 71–85.
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CD104 (Integrin β4) Antibody, anti-mouse, APC, REAfinity™, 30 µg in 1 mL
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