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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
WT1
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA925
- 标记物:
APC
- 适应物种:
human, mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
WT1 Antibody, anti-human/mouse, REAfinity™
- 抗体名:
WT1 Antibody, anti-human/mouse, REAfinity™
- 规格:
200 µL
Recombinant antibody for the detection of WT1+ cellsClone REA925 recognizes the human and mouse WT1 protein, also known as Wilms Tumor Protein 1 or Wilms tumor suppressor protein. WT1 is a transcription factor with four zinc fingers with distinct splicing isoforms. It plays an important role in cellular development and cell survival, especially in the development of the urogenital system. Furthermore, WT1 has a tumor suppressor and oncogenic role in tumor formation. WT1 is mainly expressed in kidney and on a subset of hematopoietic cells. | Additional Information: Clone REA925 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Call, K. M. et al. (1990) Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus. Cell 60 (3): 509–520. | Hamilton, T. B. et al. (1995) High affinity binding sites for the Wilms' tumour suppressor protein WT1. Nucleic Acids Res. 23 (2): 277–284. | Smolen, G. A. et al. (2004) SUMO-1 modification of the Wilms' tumor suppressor WT1. Cancer Res. 64 (21): 7846–7851.
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WT1 Antibody, anti-human/mouse, APC, REAfinity™, 200 µL
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