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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
TTF-1
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA1090
- 标记物:
Vio B515
- 适应物种:
human, mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
TTF-1 Antibody, anti-human/mouse, REAfinity™
- 抗体名:
TTF-1 Antibody, anti-human/mouse, REAfinity™
- 规格:
30 tests in 60 µL
Identification and enumeration of TTF-1+ cells by flow cytometryTTF-1 (thyroid transcripton factor-1, NKX2.1) is a homeodomain-containing transcription factor. It controls cell differentiation of telencephalic cells and is essential for proper ventral forebrain development. Furthermore, it is a key factor in the morphogenesis and differentiation of the thyroid and lung. TTF-1 is detected in primary lung adenocarcinomas and small cell carcinomas and is absent in colon and breast carcinomas. Analysis of TTF-1 expression is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating from other tumors. | Additional information: Clone REA1090 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Tanaka, H. et al. (2007) Lineage-specific dependency of lung adenocarcinomas on the lung development regulator TTF-1. Cancer Res. 67 (13): 6007–6011. | Li, Y. et al. (2013) NKX2-1 activation by SMAD2 signaling after definitive endoderm differentiation in human embryonic stem cell. Stem Cells Dev. 22 (9): 1433–1442.
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TTF-1 Antibody, anti-human/mouse, Vio® B515, REAfinity™, 30 tests in 60 µL
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