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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD10
- 亚型:
recombinant human IgG1
- 形态:
Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
- 保存条件:
避光,2-8℃
- 克隆性:
REA877
- 标记物:
pure
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Mass cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry
- 抗体英文名:
CD10 Antibody, anti-human, REAfinity™
- 抗体名:
CD10 Antibody, anti-human, REAfinity™
- 规格:
100 µg in 100 µL
Identification and enumeration of CD10+ cells by mass cytometryClone REA877 recognizes the human CD10 antigen, also known as the common acute lymphoblastic leukemia antigen (CALLA). CD10 is a 100 kDa cell surface molecule identical to human membrane-associated neutral endopeptidase (NEP) and also known as neprilysin or enkephalinase. | Human CD10 is expressed on a wide variety of normal and neoplastic cell types from different tissues including neural and hematopoietic cells. It is expressed on pre– and pro–B cells and is involved in B cell development and differentiation. The antigen is also present on mature neutrophils, T cell precursors, and some T cell leukemias/lymphomas. Furthermore, CD10 is expressed on neoplastic cells of several B lymphoid leukemias/lymphomas. | Additional information: Clone REA877 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Shipp, M. A. and Look, A. T. (1993) Hematopoietic differentiation antigens that are membrane-associated enzymes: cutting is the key! Blood 82: 1052–1070. | Kalled, S. L. et al. (1995) The distribution of CD10 (NEP 24.11, CALLA) in human and mice is similar in non-lymphoid organs but differ within the hematopoietic system: absence on murine T and B lymphoid progenitors. Eur. J. Immunol. 25: 677–687.
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CD10 Antibody, anti-human, pure, REAfinity™, 100 µg in 100 µL
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