- 询价
- Miltenyi Biotec
- 德国
- 130-134-771
- 2025年12月09日
- Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), 3D-Immunofluorescence, Immunofluorescence, Immunohistochemistry
- human cell line
- human, mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
β-Catenin
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA480
- 标记物：
Vio G570
- 适应物种：
human, mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), 3D-Immunofluorescence, Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
β-Catenin Antibody, anti-human/mouse, REAfinity™
- 抗体名：
β-Catenin Antibody, anti-human/mouse, REAfinity™
- 规格：
600 µL
Identification and enumeration of β-catenin+ cells by flow cytometryClone REA480 recognizes the human and mouse β-catenin antigen, a 92 kDa dual function protein regulating the coordination of cell-cell adhesion and gene transcription. β-catenin is a subunit of the cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. As a component of adherens junctions, β-catenin binds cadherins, Tcf family transcription factors, and the tumor suppressor adenomatous polyposis coli (APC). Mutations and overexpression of β-catenin are associated with many cancers, including hepatocellular carcinoma, colorectal carcinoma, lung cancer, malignant breast tumors as well as ovarian and endometrial cancer. | Additional information: Clone REA480 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Butz, S. et al. (1992) Plakoglobin and beta-catenin: distinct but closely related. Science 257 (5073): 1142–1144. | Clevers, H. et al. (2012) Wnt/β-catenin signaling and disease. Cell 149 (6): 1192–1205. | MacDonald, B. T. et al. (2009) Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev. Cell 17 (1): 9–26.
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β-Catenin Antibody, anti-human/mouse, Vio® G570, REAfinity™, 600 µL
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