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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
TOM22
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA1185
- 标记物:
PE
- 适应物种:
human, mouse, rat
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
TOM22 Antibody, anti-human/mouse, REAfinity™
- 抗体名:
TOM22 Antibody, anti-human/mouse, REAfinity™
- 规格:
100 tests in 200 µL
Identification and enumeration of TOM22+ cells by flow cytometryClone REA1185 recognizes the human and mouse mitochondrial import receptor subunit TOM22 homolog antigen, a single-pass membrane protein which is also known as translocase of outer membrane 22 kDa subunit homolog. TOM22 is a central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. It functions together with the peripheral receptor TOM20 as the transit peptide receptor and facilitates the movement of pre-proteins into the translocation pore. | Additional information: Clone REA1185 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Shiota, T. et al. (2011) In vivo protein-interaction mapping of a mitochondrial translocator protein Tom22 at work. Proc. Natl. Acad. Sci. U.S.A. 108 (37): 15179–15183. | Bellot, G. et al. (2007) TOM22, a core component of the mitochondria outer membrane protein translocation pore, is a mitochondrial receptor for the proapoptotic protein Bax. Cell Death Differ. 14 (4): 785–794. | Yano, M. et al. (2000) Identification and functional analysis of human Tom22 for protein import into mitochondria. Mol. Cell. Biol. 20 (19): 7205–7213.
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TOM22 Antibody, anti-human/mouse, PE, REAfinity™, 100 tests in 200 µL
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