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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
TLT-2
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA514
- 标记物:
Vio Bright V423
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 抗体英文名:
TLT-2 Antibody, anti-human, REAfinity™
- 抗体名:
TLT-2 Antibody, anti-human, REAfinity™
- 规格:
30 tests in 60 µL
Identification and enumeration of TLT-2+ cells by flow cytometryClone REA514 recognizes the human Trem-like transcript 2 (TLT-2) antigen, a single-pass type I membrane protein, which is also known as triggering receptor expressed on myeloid cells-like protein 2 (TREML2). TLT-2 is one of the conserved TREM family members, which is expressed on B cells, T cells, macrophages, and neutrophils. It is suggested to play an important role in the immune system, for it is not only highly expressed in inflammation, but also promotes the proliferation of T cells and the production of cytokines. | Additional information: Clone REA514 displays negligible binding to Fc receptors
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文献和实验该产品被引用文献
Halpert, M. M. et al. (2011) TLT2 potentiates neutrophil antibacterial activity and chemotaxis in response to G protein-coupled receptor-mediated signaling. J Immunol 187 (5): 2346–2355. | Hashiguchi, M. et al. (2008) Triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses. Proc. Natl. Acad. Sci. U.S.A. 105 (30): 10495–10500. | Allcock, R. J. et al. (2003) The human TREM gene cluster at 6p21.1 encodes both activating and inhibitory single IgV domain receptors and includes NKp44. Eur. J. Immunol. 33 (2): 567–577.
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TLT-2 Antibody, anti-human, Vio® Bright V423, REAfinity™, 30 tests in 60 µL
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