- 询价
- Miltenyi Biotec
- 德国
- 130-116-638
- 2025年12月09日
- Flow cytometry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
TIM-4
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA999
- 标记物：
PE-Vio 615
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 抗体英文名：
TIM-4 Antibody, anti-mouse, REAfinity™
- 抗体名：
TIM-4 Antibody, anti-mouse, REAfinity™
- 规格：
150 µg in 1 mL
Identification and enumeration of TIM-4+ cells by flow cytometryClone REA999 recognizes the mouse antigen TIM-4, which is also known as T cell immunoglobulin and mucin domain-containing protein 4 or spleen, mucin-containing, knockout of lymphotoxin protein (SMUCKLER). TIM-4 is a member of the TIM gene family, which is involved in a variety of immunity related processes including T cell proliferation and survival, tissue inflammation, and atopy. In mice, eight TIM genes encode the proteins TIM-1 to TIM-8, whereas only three TIM genes are found in humans encoding TIM-1, TIM-3, and TIM-4. In spleen, TIM-4 is expressed on antigen presenting cells such as lymphoid and myeloid dendritic cells and macrophages but not by T or B lymphocytes.
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文献和实验该产品被引用文献
Shakhov, A. N. et al. (2004) SMUCKLER/TIM4 is a distinct member of TIM family expressed by stromal cells of secondary lymphoid tissues and associated with lymphotoxin signaling. Eur. J. Immunol. 34 (2): 494–503. | Miyanishi, M. et al. (2007) Identification of Tim4 as a phosphatidylserine receptor. Nature 450 (7168): 435–439. | Rodriguez-Manzanet, R. et al. (2008) TIM-4 expressed on APCs induces T cell expansion and survival. J Immunol 180 (7): 4706–4713.
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TIM-4 Antibody, anti-mouse, PE-Vio® 615, REAfinity™, 150 µg in 1 mL
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