- 询价
- Miltenyi Biotec
- 德国
- 130-115-023
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
TGF-β RII
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA903
- 标记物：
FITC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
TGF-β RII Antibody, anti-human, REAfinity™
- 抗体名：
TGF-β RII Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of TGF-β RII+ cells by flow cytometryClone REA903 recognizes the human transforming growth receptor beta 2 (TGF-β RII) antigen, a single-pass transmembrane protein belonging to the superfamily of serine/threonine kinase receptors. Members of this family bind different TGF-β cytokines (TGF-β1, TGF-β2, TGF-β3) and other growth factors and cytokine signaling proteins. The association between TGF-β RII and TGF-β2 phosphorylates proteins, that regulate the transcription of a subset of genes related to cell proliferation in the nucleus. | Additional information: Clone REA903 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Doré, J. J. et al. (1998) Heteromeric and homomeric transforming growth factor-beta receptors show distinct signaling and endocytic responses in epithelial cells. J. Biol. Chem. 273 (48): 31770–31777. | Rys, J. P. et al. (2015) Discrete spatial organization of TGFβ receptors couples receptor multimerization and signaling to cellular tension. Elife 4: . | Narushima, Y. et al. (2016) Integrative network analysis combined with quantitative phosphoproteomics reveals transforming growth factor-beta receptor type-2 (TGFBR2) as a novel regulator of glioblastoma stem cell properties. Mol. Cell. Proteomics 15 (3): 1017–1031.
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TGF-β RII Antibody, anti-human, FITC, REAfinity™, 100 tests in 200 µL
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