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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
TCRγ/δ
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA591
- 标记物:
PE-Vio 770
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, Mass cytometry
- 浓度:
1:50
- 抗体英文名:
TCRγ/δ Antibody, anti-human, REAfinity™
- 抗体名:
TCRγ/δ Antibody, anti-human, REAfinity™
- 规格:
30 tests in 60 µL
Identification and enumeration of TCRγ/δ+ cells by flow cytometryClone REA591 recognizes the human TCRγ/δ antigen. The T cell receptor is a heterodimeric glycoprotein associated with the CD3 antigen. It consists of an α and a β chain (TCRα/β) or a γ and a δ chain (TCRγ/δ). The γ and δ TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. The γ chain forms either disulfide-linked or non-disulfide–linked heterodimers with the δ-subunit. The γ/δ T cell receptor is present on a subset of T lymphocytes in peripheral blood. TCRγ/δ is involved in the antigen recognition of tumor-associated antigens or bacterial antigens presented by MHC class I molecules. | Additional information: Clone REA591 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Airoldi, I. et al. (2015) γδ T-cell reconstitution after HLA-haploidentical hematopoietic transplantation depleted of TCR-αβ+/CD19+ lymphocytes. Blood 125 (15): 2349–2358. | Bonneville, M. et al. (2010) Gammadelta T cell effector functions: a blend of innate programming and acquired plasticity. Nat. Rev. Immunol. 10 (7): 467–478. | Wiest, D. L. (2016) Development of γδ T cells, the special-force soldiers of the immune system. Methods Mol. Biol. 1323: 23–32.
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TCRγ/δ Antibody, anti-human, PE-Vio® 770, REAfinity™, 30 tests in 60 µL
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