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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
TCR Vβ5.3
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA670
- 标记物:
Biotin
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry
- 浓度:
1:11
- 抗体英文名:
TCR Vβ5.3 Antibody, anti-human, REAfinity™
- 抗体名:
TCR Vβ5.3 Antibody, anti-human, REAfinity™
- 规格:
30 tests in 300 µL
Identification and enumeration of TCR Vβ5.3+ cells by flow cytometryClone REA670 recognizes the human variable beta 5.3 subunit of the α/β T cell receptor (TCR Vβ5.3), a member of the Ig superfamily. The TCR is a heterodimeric glycoprotein associated with the CD3 antigen. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ5.3 is a variant of the TCR β chain. α/β T cells express a diverse α/β TCR repertoire that specifically co-recognizes self or foreign antigen bound to antigen-presenting molecules, which thereby leads to T cell–mediated immunity. TCR Vβ5.3 is expressed on a subset of peripheral blood T cells. | Additional information: Clone REA670 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Born, W. et al. (1985) Rearrangement of T-cell receptor beta-chain genes during T-cell development. Proc. Natl. Acad. Sci. U.S.A. 82 (9): 2925–2929. | Bleux, C. et al. (1995) A mouse monoclonal antibody specific for the V beta 5.3 chain of the human TcR recognizes a subgroup of the mouse TcR V beta 8.2 chains. J Leukoc Biol 57 (3): 491–491. | Adari, H. et al. (1995) Expression of the human T-cell receptor V beta 5.3 in Escherichia coli by thermal induction of the trc promoter: nucleotide sequence of the lacIts gene. DNA Cell Biol. 14 (11): 945–950.
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TCR Vβ5.3 Antibody, anti-human, Biotin, REAfinity™, 30 tests in 300 µL
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