TCR Vβ5.3 Antibody, anti-human

Identification and enumeration of TCR Vβ5.3+ cells by flow cytometryClone REA670 recognizes the human variable beta 5.3 subunit of the α/β T cell receptor (TCR Vβ5.3), a member of the Ig superfamily. The TCR is a heterodimeric glycoprotein associated with the CD3 antigen. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ5.3 is a variant of the TCR β chain. α/β T cells express a diverse α/β TCR repertoire that specifically co-recognizes self or foreign antigen bound to antigen-presenting molecules, which thereby leads to T cell–mediated immunity. TCR Vβ5.3 is expressed on a subset of peripheral blood T cells. | Additional information: Clone REA670 displays negligible binding to Fc receptors.