TCR Vβ11 Antibody, anti-mouse,

Identification and enumeration of TCR Vβ11+ cells by flow cytometryClone REA657 recognizes the mouse V beta 11 T cell receptor (TCR Vβ11). The T cell receptor (TCR) is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. T cells expressing this receptor are referred to as TCRα/β T cells, though a minority of T cells express an alternate receptor, formed by variable gamma and delta chains, referred as TCRγ/δ T cells. TCR Vβ11 is a variant of the TCR β chain and is expressed on mouse strains with the b haplotype in the TCR β gene complex, including C57BL/6 and B10, but not on mice strains with the a haplotype, including C57L, SJL, and SWR. | Additional information: Clone REA657 displays negligible binding to Fc receptors.