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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
TCR Vβ10
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA651
- 标记物:
APC
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:10
- 抗体英文名:
TCR Vβ10 Antibody, anti-mouse, REAfinity™
- 抗体名:
TCR Vβ10 Antibody, anti-mouse, REAfinity™
- 规格:
9 µg in 300 µL
Identification and enumeration of TCR Vβ10+ cells by flow cytometryClone REA651 recognizes the mouse V beta 10 T cell receptor (TCR Vβ10). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ10 is a variant of the TCR β chain and is expressed on T cells having the a haplotype, but not with the b and c haplotype of the TCRβ gene complex. | Additional information: Clone REA651 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Bour, H. et al. (1999) Dramatic influence of V beta gene polymorphism on an antigen-specific CD8+ T cell response in vivo. J Immunol 162 (8): 4647–4656. | Brenden, N. et al. (1999) Differential MHC expression requirements for positive selection of separate TCR Vb families. Immunogenetics 49 (1): 1–6. | Deepe, G. S. Jr. et al. (2002) Discordance between T-cell receptor expression and effector function in mice infected with Histoplasma capsulatum. Infect. Immun. 70 (3): 1648–1652.
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TCR Vβ10 Antibody, anti-mouse, APC, REAfinity™, 9 µg in 300 µL
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