- 询价
- Miltenyi Biotec
- 德国
- 130-106-054
- 2025年12月09日
- Flow cytometry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
TCR Vα3.2 (b, c)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA395
- 标记物：
APC
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:10
- 抗体英文名：
TCR Vα3.2 (b, c) Antibody, anti-mouse, REAfinity™
- 抗体名：
TCR Vα3.2 (b, c) Antibody, anti-mouse, REAfinity™
- 规格：
9 µg in 300 µL
Identification and enumeration of TCR Vα3.2 (b, c)+ cells by flow cytometryClone REA395 recognizes the mouse Vα 3.2 T cell receptor (TCR Vα3.2) of mice having the b (e.g., C57BL/6) and c (e.g., SJL, NOD) haplotypes, but not with the strains having the a (Balb/c) or d (DBA/2) haplotype. The TCR is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. TCR Vα elements are expressed preferentially in CD4 or CD8 subsets in a manner that is largely independent of the MHC haplotype. It is likely that the Vα elements interact preferentially with conserved regions of class I or class II molecules. | Additional information: Clone REA395 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Sim, B. C. et al. (1997) V alpha 3.2 selection in MHC class I mutant mice: evidence for an alternate orientation of TCR-MHC class I interaction. J Immunol 159 (7): 3322–3329. | Pereira, P. et al. (1997) The T cell receptor repertoire of intestinal intraepithelial gammadelta T lymphocytes is influenced by genes linked to the major histocompatibility complex and to the T cell receptor loci. Proc. Natl. Acad. Sci. U.S.A. 94 (11): 5761–5766. | von Essen, M. R. et al. (2012) Mechanisms behind functional avidity maturation in T cells. Clin. Dev. Immunol. 2012: 163453.
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TCR Vα3.2 (b, c) Antibody, anti-mouse, APC, REAfinity™, 9 µg in 300 µL
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