- 询价
- Miltenyi Biotec
- 德国
- 130-107-004
- 2025年12月09日
- Flow cytometry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
TCR Vα11.1, 11.2
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA464
- 标记物：
APC-Vio 770
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:10
- 抗体英文名：
TCR Vα11.1, 11.2 Antibody, anti-mouse, REAfinity™
- 抗体名：
TCR Vα11.1, 11.2 Antibody, anti-mouse, REAfinity™
- 规格：
9 µg in 300 µL
Identification and enumeration of TCR Vα11.1, 11.2+ cells by flow cytometryClone REA464 recognizes the mouse V alpha 11.1 and 11.2 T cell receptor (TCR Vα11.1, 11.2) of mice having the b (e.g., C57BL/6) and d (e.g., DBA/1, DBA/2, NZW) haplotypes, but not with the strains having the a (Balb/c) or c (e.g., SJL, NOD) haplotype. The TCR is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. TCR Vα elements are expressed preferentially in CD4 or CD8 subsets in a manner that is largely independent of the MHC haplotype. It is likely that the Vα elements interact preferentially with conserved regions of class I or class II molecules. | Additional information: Clone REA464 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Osman, G. E. et al. (1998) Expression of a type II collagen-specific TCR transgene accelerates the onset of arthritis in mice. Int. Immunol. 10 (11): 1613–1622. | Nakajima, P. B. et al. (1992) Chromosome 14 in B10.A(18R) mice is recombinant and includes Tcra-Va alleles. Immunogenetics 35 (3): 190–198. | Osman, G. E. et al. (1999) T-cell receptor vbeta deletion and valpha polymorphism are responsible for the resistance of SWR mouse to arthritis induction. Immunogenetics 49 (9): 764–772.
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文献支持
TCR Vα11.1, 11.2 Antibody, anti-mouse, APC-Vio® 770, REAfinity™, 9 µg in 300 µL
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