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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
STAT5 pY694
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA1371
- 标记物:
PE
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Intracellular flow cytometry
- 浓度:
1:50
- 抗体英文名:
STAT5 pY694 Antibody, anti-human, REAfinity™
- 抗体名:
STAT5 pY694 Antibody, anti-human, REAfinity™
- 规格:
30 tests in 60 µL
Identification and enumeration of STAT5 pY694+ cells by flow cytometryClone REA1371 recognizes the human STAT5 antigen phosphorylated at tyrosine 694, a member of signal transducers and activators of the transcription (STAT) family. The seven STAT family members play a critical role in activation of signaling pathways in response to the presence of various cytokines and growth factors (interferon (IFN)-α, IFN-γ, EGF, PDGF, and interleukin (IL)-6). It has been found in cancer cells. STAT5 is encoded by two separate genes, Stat5a and Stat5b that share high similarity. | Additional Information: Clone REA1371 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Van De Wiele, C. J. et al. (2004) Thymocytes between the beta-selection and positive selection checkpoints are nonresponsive to IL-7 as assessed by STAT-5 phosphorylation. J Immunol 172 (7): 4235–4244. | Bromberg, J. et al. (2000) The role of STATs in transcriptional control and their impact on cellular function. Oncogene 19 (21): 2468–2473. | Cumaraswamy, A. A. et al. (2014) Nanomolar-Potency Small Molecule Inhibitor of STAT5 Protein. ACS Med Chem Lett 5 (11): 1202–1206.
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STAT5 pY694 Antibody, anti-human, PE, REAfinity™, 30 tests in 60 µL
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