- 询价
- Miltenyi Biotec
- 德国
- 130-114-683
- 2025年12月09日
- Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
STAT4 pY693
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA855
- 标记物：
PE
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
STAT4 pY693 Antibody, anti-human, REAfinity™
- 抗体名：
STAT4 pY693 Antibody, anti-human, REAfinity™
- 规格：
30 tests in 60 µL
Identification and enumeration of STAT4 pY693+ cells by flow cytometryClone REA855 recognizes the human signal transducer and activator of transcription 4 (STAT4) antigen phosphorylated at tyrosine 693 (pY693). STAT4 is a member of signal transducers and activators of the transcription (STAT) family. STAT proteins transmit signals from a receptor complex to the nucleus and activate gene expression. The seven STAT family members play a critical role in activation of signaling pathways in response to the presence of various cytokines and growth factors (interferon α (IFN-α), interferon γ (IFN-γ), EGF, PDGF, and interleukin 6 (IL-6)). STAT4 is involved in the development of Tʜ1 cells from naive CD4+ T cells and IFN-γ production in response to IL-12. | Additional information: Clone REA855 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Yamamoto, K. et al. (1994) Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation. Mol. Cell. Biol. 14 (7): 4342–4349. | Bacon, C. M. et al. (1995) Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes. Proc. Natl. Acad. Sci. U.S.A. 92 (16): 7307–7311. | Kaplan, M. H. (2005) STAT4: a critical regulator of inflammation in vivo. Immunol. Res. 31 (3): 231–242.
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STAT4 pY693 Antibody, anti-human, PE, REAfinity™, 30 tests in 60 µL
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